Oxytocin depolarizes mitochondria in isolated myometrial cells
نویسندگان
چکیده
منابع مشابه
Oxytocin-Stimulated NFAT Transcriptional Activation in Human Myometrial Cells
Oxytocin (OXT) is a peptide hormone that binds the OXT receptor on myometrial cells, initiating an intracellular signaling cascade, resulting in accumulation of intracellular calcium and smooth muscle contraction. In other systems, an elevation of intracellular Ca(2+) stimulates nuclear translocation of the transcription factor, nuclear factor of activated T cells (NFAT), which is transcription...
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Regulators of G protein signaling (RGS proteins) interact with Galpha(q) and Galpha(i) and accelerate GTPase activity. These proteins have been characterized only within the past few years, so our understanding of their importance is still preliminary. We examined the effect of oxytocin on RGS2 mRNA expression to help determine the role of RGS proteins in oxytocin signaling in human myometrial ...
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ژورنال
عنوان ژورنال: Experimental Physiology
سال: 2011
ISSN: 0958-0670
DOI: 10.1113/expphysiol.2011.058388